Semaglutide is one of the most popular and effective peptides for weight loss. Originally developed to treat type 2 diabetes, it helps regulate blood sugar and curb appetite, which leads to gradual and sustainable fat loss. It's often used under brand names like Ozempic and Wegovy. It's typically injected once a week and works well as part of a long-term weight loss plan. Many users see noticeable changes in their weight, energy, and confidence after just a few weeks of consistent use.